Vampire; the Requiem, with leather jackets, psychobilly music, motorcycles, pompadours, hot rods, and stupid B movie monsters.
It would be a game about undead superheroes with fangs, zero morality, and lots of kitschy horror imagery. I imagine the player characters would be a vampire gang, and the primary antagonists would be other vampire gangs, or the vampire police, with occasional battles against Frankenstein's monster and werewolf gangs.
I think I just might write this up.